VISDB Viral Integration Site DataBase

VIS ID

TVIS10015225

Fusion event

HBV-RABGAP1L integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

1178

Orient

-

Integrated sequence

ATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGC| |CAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGG

Chromosome

chr1

Cytoband

q25.1

Reference genome

Start

End

174619720/174650582 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-4504 ; hsa-mir-4778-3p ; hsa-mir-676-5p ; hsa-mir-4714-3p ; hsa-mir-34c-3p ; hsa-mir-7161-3p ; hsa-mir-3156-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-378a-5p ; hsa-mir-6802-5p ; hsa-mir-6800-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-6759-3p ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4781-3p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-576-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-1297 ; hsa-mir-1343-3p ; hsa-mir-1976 ; hsa-mir-23a-5p ; hsa-mir-23b-5p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-4279 ; hsa-mir-4465 ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-6513-3p ; hsa-mir-660-3p ; hsa-mir-6727-3p ; hsa-mir-6742-3p ; hsa-mir-6747-3p ; hsa-mir-6783-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6852-5p ; hsa-mir-8062 ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-101-1/Upstream/2505938; hsa-mir-1182/Downstream/1317788;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/490673, chr1-CpG: 121/Downstream/348771

Upstream sequence

aagctattgattattgccacaatttcagagcctgttattggtctattcagagattcaacttcttcctggtttagtcttgggagggtgtacgtgtcgagga

Downstream sequence

atttatccatttcttctagattttctagtttatttgtgtagaggtatttgtagtattctctgatggtagtttgtatttctgtgggatcggtggtgatatc