ADRA1B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015229
Fusion event
HBV-ADRA1B integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
1891
Orient
+
Integrated sequence
TAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT| |GGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCT
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
159412324/159985317 (Hg38)
End
159412324/159985317 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADRA1B
miRNAs that regulate target gene
hsa-mir-10b-5p
Nearest miRNA
hsa-mir-10397/Upstream/5155777; hsa-mir-103a-1/Downstream/489085;
Nearest TSS
ENST00000502646/Upstream/47551; ENST00000520274/Downstream/23796;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/12396, chr5-CpG: 47/Downstream/1722
Nearby gene
ADRA1B
Upstream sequence
cctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaacccta
Downstream sequence
tatgggttatctcctccattggaatatgaaatccaccttagcaagtactttaattactttggttacttctggattcctgtatcagggaataataactggc
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate