C8orf34 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015232
Fusion event
HBV-C8orf34 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
253
Orient
-
Integrated sequence
AACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAG| |ACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCC
Host Sequence
Chromosome
chr8
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
69523491/68611256 (Hg38)
End
69523491/68611256 (Hg38)
Orient
-
Location type
Intronic
Target gene
C8orf34
Nearest miRNA
hsa-mir-124-1/Upstream/4231999; hsa-mir-10400/Downstream/5937287;
Nearest TSS
ENST00000518652/Upstream/78236; ENST00000325233/Downstream/14203;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/279688, chr8-CpG: 224/Downstream/1220607
Upstream sequence
ctctggccagtgagaaggaggtagaagttggtaagtgtggcaccctggagcacatcataagaaagatagccttagagattttgcctcttccctctgcttc
Downstream sequence
AAATGTTTTGGCAGAAATATGAAAACTGATGAGCTTTTTACATGAAACATAGGACTGACTGCTATATTTGTTCTCCTTGGTTGTCAATTCAGTTCAACTG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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