C8orf34 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015233
Fusion event
HBV-C8orf34 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp3 X protein
Start
1429
Orient
-
Integrated sequence
GGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTA| |CGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGC
Host Sequence
Chromosome
chr8
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
69528052/68615817 (Hg38)
End
69528052/68615817 (Hg38)
Orient
+
Location type
Intronic
Target gene
C8orf34
Nearest miRNA
hsa-mir-124-1/Upstream/4236560; hsa-mir-10400/Downstream/5932726;
Nearest TSS
ENST00000518652/Upstream/82797; ENST00000325233/Downstream/9642;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/284249, chr8-CpG: 224/Downstream/1216046
Upstream sequence
AATCAGACAAATGCTGAATATATTTGCAGTAAATCACTAAAAAAATAAAAAAAATTAGAATACTGAGGTATCTTACGGGCTTAATATTTCCTGGTGGTTA
Downstream sequence
gaggattccctctttttctattgattggaatagtttcagaaggaatggtaccagttcctccttgtacctctggtagaattcggctgtgaatccatctggt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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