Basic Information
VIS ID
TVIS10015241
Fusion event
HBV-chr2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1752
Orient
-
Integrated sequence
TACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGA| |GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT
Host Sequence
Chromosome
chr2
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
207883313/207018589 (Hg38)
End
207883313/207018589 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/235281; hsa-mir-1244-1/Downstream/91398;
Nearest TSS
ENST00000437798/Upstream/79035; ENST00000435643/Downstream/105819;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/253153, chr2-CpG: 75/Downstream/147539
Nearby gene
CPO(No orient, 49114)
Upstream sequence
caccctccattcctctttcttctcccttagcctctgttcttaagaacataaaacctcttcaactctcacctgacctaaaacctaaatgccttattttctt
Downstream sequence
ctacaatgccgtttgaccccaatacaaactagacagtggttctaaatggccagaaaacggcacttccaatttctccatcctacaagacctaaataatttt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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