Basic Information
VIS ID
TVIS10015244
Fusion event
HBV-LOC101928516 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
2680
Orient
-
Integrated sequence
ATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCA| |TTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTAT
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
74850223/74140507 (Hg38)
End
74850223/74140507 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6D
Target gene
LOC101928516
Nearest miRNA
hsa-mir-10398/Upstream/1172754; hsa-mir-10524/Downstream/1287900;
Nearest TSS
ENST00000381078/Upstream/71056; ENST00000421318/Downstream/454706;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/444096, chr6-CpG: 28/Downstream/944657
Upstream sequence
CCCGTATACCCACTTGGTATACGTTAAACAGGAGGGCTCAAGAAATAACAATGTGCTATGAATACACTGCAACAAGTTAGCAATTTACATTTACAGGATT
Downstream sequence
atgtgtaataaaaaccaacctTTTTGTTAAAGGGTAGAACAGAAGAAGTAGAGAAACCAGTACTCAGCCTATCCCTCAATAGATTTTTTTACTTATGTAC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate