VISDB Viral Integration Site DataBase

VIS ID

TVIS10015246

Fusion event

HBV-LARP4B integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2

Start

241

Orient

+

Integrated sequence

GACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATAC| |CGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACC

Chromosome

chr10

Cytoband

p15.3

Reference genome

Start

End

879223/833283 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-30a-5p ; hsa-let-7d-5p ; hsa-mir-218-5p ; hsa-mir-4642 ; hsa-mir-542-3p ; hsa-mir-4504 ; hsa-mir-3622b-5p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-4715-5p ; hsa-mir-106a-3p ; hsa-mir-191-3p ; hsa-mir-603 ; hsa-mir-6776-3p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-6822-3p ; hsa-mir-21-3p ; hsa-mir-3591-3p ; hsa-mir-4768-5p ; hsa-mir-6833-3p ; hsa-mir-6873-3p

Nearest miRNA

hsa-mir-5699/Upstream/191505; hsa-mir-107/Downstream/1242736;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/23338, chr10-CpG: 134/Downstream/98066

Upstream sequence

gaagtagaagaattgtcttgggccacacataaaatacactaacactaacgatagctgatgagctttaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

Downstream sequence

acctcaaaatgtttgaagaaagtttacgcatttgtgttgagctgcatacaaagccgtcctgggcggcatgccgcccacgggctgAAGAAGCATGccctaa