Basic Information
VIS ID
TVIS10015250
Fusion event
HBV-LOC105377795 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1718
Orient
-
Integrated sequence
ACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACT| |GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG
Host Sequence
Chromosome
chr8
Cytoband
p23.2
Reference genome
GRCh37/hg19
Start
5841656/5984134 (Hg38)
End
5841656/5984134 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377795
Nearest miRNA
hsa-mir-3674/Upstream/3907494; hsa-mir-10400/Downstream/637990;
Nearest TSS
ENST00000518652/Upstream/314057; ENST00000522905/Downstream/52840;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/860710, chr8-CpG: 72/Downstream/421927
Upstream sequence
TATTATTCAGGAAGATATTTGGTTTTCAGCTTTCCCTTGATGGTTTTTGTCTTTTTATTCCCATTCATTGAACAAATGTTAATTTTTTCTTTTCACTCtc
Downstream sequence
atcaataaccatcttaaaacttaaagaaaaaacaaagagcaaactgaacccaaaacaagcacaaggaaaaaactaatgaagattagagtagaaatacaca
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate