VISDB Viral Integration Site DataBase

VIS ID

TVIS10015251

Fusion event

HBV-SGK3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

1851

Orient

+

Integrated sequence

AGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGT| |TCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCT

Chromosome

chr8

Cytoband

q13.1

Reference genome

Start

End

67632214/66719979 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-1-3p ; hsa-mir-96-5p ; hsa-mir-16-5p ; hsa-mir-708-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-2681-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-5003-3p ; hsa-mir-6848-3p ; hsa-mir-5587-5p ; hsa-mir-6843-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-6801-5p ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-4716-5p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-4781-3p ; hsa-mir-212-3p

Nearest miRNA

hsa-mir-124-1/Upstream/2340722; hsa-mir-10400/Downstream/7828564;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/6790, chr8-CpG: 57/Downstream/55091

Upstream sequence

AAAATGAAAACACAGTGAGTCTTATGTGGTTCCACAACAATAATGAAGTATAAAATTTAATAATATACCAGTGTGTGCCACACAAAATCATAAATGATGA

Downstream sequence

atcacacttacgtagccagccaacgtcacagattccatgcacctttgaaccagttattttactgtttcctggccacctgccatgccccagccctggctaa