Fusion event
HBV-LOC105375631 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
HBVgp3 X protein;HBVgp4 precore/core protein
Integrated sequence
TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTAT
End
90411435/89399206 (Hg38)
Nearest miRNA
hsa-mir-12123/Upstream/9157733; hsa-mir-10400/Downstream/1806279;
Upstream sequence
GCAGGGCAGCTTTTGCTGGACAGCAAAAGGACCCACCTGCACAGCTACCAAAGTGCTCTATGTATATTTTAAGAAGGCTCGTCTCAAATTCAACAAATGC
Downstream sequence
AAGATTCTGTTGGTTTGTTTTAATTTTATTCTTTATCTGGAATTATAGTAGTAATCTATTCATTCTGTAAATATTCAAGGCAAAAGAAGAATCTAAAGTA
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.