VISDB Viral Integration Site DataBase

VIS ID

TVIS10015254

Fusion event

HBV-SLC25A32 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein;HBVgp4 precore/core protein

Start

1834

Orient

+

Integrated sequence

GGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCT| |GCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGC

Chromosome

chr8

Cytoband

q22.3

Reference genome

Start

End

104412731/103400503 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-mir-16-5p ; hsa-mir-578 ; hsa-mir-4775 ; hsa-mir-9-3p ; hsa-mir-5681b ; hsa-mir-590-3p ; hsa-mir-4422 ; hsa-mir-6835-3p ; hsa-mir-25-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-141-5p ; hsa-mir-4795-3p ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-668-3p ; hsa-mir-194-5p ; hsa-mir-3137 ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-339-5p ; hsa-mir-4704-3p ; hsa-mir-483-3p ; hsa-mir-501-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6499-3p ; hsa-mir-4722-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6134 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-1247-3p ; hsa-mir-4768-3p

Nearest miRNA

hsa-mir-12123/Upstream/245814; hsa-mir-10400/Downstream/1083866;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/28631, chr8-CpG: 98/Downstream/14163

Upstream sequence

gatgagtatttcaagcatgaagTATCAATACTAACAGCAATAAGTAAATTGGATTTAGCTTTTAAAAGCTCTTTGGTGGTACCCTTTTTTAAAAAAAATT

Downstream sequence

ATTAGGAGCAATTCCCTTGTAAAATCCACCGACGCCTTCTTTCCTTTAGAGGGAAAAATAGATAATGCTTAATTTTGTATAGAGCTAGCTTGAAAACACG