Basic Information
VIS ID
TVIS10015256
Fusion event
HBV-LOC101927413 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein;HBVgp4 precore/core protein
Start
1828
Orient
+
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
109956262/108944033 (Hg38)
End
109956262/108944033 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC101927413
Nearest miRNA
hsa-mir-12123/Upstream/4459568; hsa-mir-10400/Downstream/3699460;
Nearest TSS
ENST00000518652/Upstream/25420; ENST00000518632/Downstream/119384;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/156420, chr8-CpG: 81/Downstream/389654
Upstream sequence
TCCGAAAATCTGGGAAAGGAGAATATGGGACAATAAACAAAGCCCAGTCCCATGCCTCCCTCTTAGCCATCTGCTATACCATCTACGAAACCACACCATT
Downstream sequence
TTGTAACAGCTATAGTTTCCACACCACAGCATAACTCAGGACATTAAAGGTACTACAGACAACTCAATGTATGCAAACCACAATGACTAACCCTGGAACC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate