Fusion event
HBV-TERT integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
HBVgp3 X protein
Integrated sequence
CCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGG| |ACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTT
End
1295518/1295403 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-4635/Upstream/232429; hsa-mir-10397/Downstream/13907;
Nearest cancer related gene
Upstream sequence
ctgggcatggtggctcacacctattcccagcacttcgggaagccgaggcaggcagatcatctgaagtcaggagttcgagaacagactggccaacatggca
Downstream sequence
CGAATCGGCCTAGGCTGTGGGGTAACCCGAGGGAGGGGCCATGATGTGGAGGCCCTGGGAACAGGTGCGTGCGGCGACCCTTTGGCCGCTGGCCTGATCC
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.