VISDB Viral Integration Site DataBase

VIS ID

TVIS10015265

Fusion event

HBV-GABRB3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2

Start

543

Orient

-

Integrated sequence

TCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAA| |GGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTAT

Chromosome

chr15

Cytoband

q12

Reference genome

Start

End

27031371/26786224 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-125b-5p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-3177-5p ; hsa-mir-3163 ; hsa-mir-5582-3p ; hsa-mir-552-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-3678-3p ; hsa-mir-1273h-3p ; hsa-mir-6802-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-298 ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-4691-3p ; hsa-mir-497-3p ; hsa-mir-424-3p ; hsa-mir-4703-3p ; hsa-mir-520d-5p ; hsa-mir-524-5p

Nearest miRNA

hsa-mir-1268a/Upstream/937399; hsa-mir-10393/Downstream/1640267;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/12351, chr15-CpG: 17/Downstream/52621

Upstream sequence

gatgttcctagatgtgcttttttgttgatccttcttggaattcatcgagcttctcaggtctgtgtgtttatagctttcatctcatttggataatttccag

Downstream sequence

ctaacattttcaaaaacatttttcctcccttcttgggaaactccaattacacatatgtgtgacacttcgatatagtctcacaggcctctgaatactttat