Fusion event
HBV-GABRB3 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S
Integrated sequence
AGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGAC| |CCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGC
End
27031546/26786399 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1268a/Upstream/937574; hsa-mir-10393/Downstream/1640092;
Upstream sequence
tctcacaggcctctgaatactttatttttttcagtgtgtttttccactgtgctttagttcagatagccatattattatgttttcaagttGTCTTTTTAAA
Downstream sequence
ACCTTTATatttttatgtttacacagtaggtatatgtatttatgtggtacatattttggtacacgcatacaacgcatactgattacatcaaggtaaatgg
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.