VISDB Viral Integration Site DataBase

VIS ID

TVIS10015267

Fusion event

HBV-ESRRG integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp4 precore/core protein

Start

2368

Orient

+

Integrated sequence

GGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCC| |CTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTC

Chromosome

chr1

Cytoband

q41

Reference genome

Start

End

217303046/217129704 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-205-5p ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6815-3p ; hsa-mir-2115-5p ; hsa-mir-5580-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-935 ; hsa-mir-320a

Nearest miRNA

hsa-mir-101-1/Upstream/5052019; hsa-mir-1182/Downstream/2988149;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/39832, chr1-CpG: 99/Downstream/4698

Upstream sequence

cagcgataaagagggatgaagaactgactcatgttacaatatggatgaaccttcataacaaatgaagttatatgaagataataagagaaagaagccagat

Downstream sequence

acaaaaggccaaatgttaaatgattccaactataaaatgtccagaataggcaaacccatagagacagaaagcagattaaggcttgacagtggctgaaggg