Basic Information
VIS ID
TVIS10015270
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1710
Orient
-
Integrated sequence
TGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTT| |CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA
Host Sequence
Chromosome
chr1
Cytoband
p12
Reference genome
GRCh37/hg19
Start
118200636/117658014 (Hg38)
End
118200636/117658014 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/563286; hsa-mir-1182/Downstream/28192573;
Nearest TSS
ENST00000473358/Upstream/52080; ENST00000471680/Downstream/229719;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/50968, chr1-CpG: 73/Downstream/271203
Nearby gene
TENT5C(No orient, 29624)
Upstream sequence
taattatttttattttttaatttttaaaaaatttttttCACAAAATTattcactcattttatacacatttttgagctcataccatgtgccaggcattggg
Downstream sequence
ctacaaagatgaaaaagacatcaatccATTTTTATTTTTCAATATATTTCCCAGAACTTGTGTCATCTTAGGAGTGTCCGTGCTGCTGATTGGGCTCAGG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate