Basic Information
VIS ID
TVIS10015275
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1798
Orient
+
Integrated sequence
TGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTG| |GTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTG
Host Sequence
Chromosome
chr6
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
30481176/30513399 (Hg38)
End
30481176/30513399 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-3143/Upstream/3365711; hsa-mir-10398/Downstream/70933;
Nearest TSS
ENST00000381078/Upstream/23887; ENST00000415195/Downstream/2867;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/23001, chr6-CpG: 20/Downstream/42110
Nearby gene
LINC02569(+2867) ;
Upstream sequence
taacctttaagaaataccatttgtgctttgatgtagtaccaaagaataattacgttatctgaaaaagccatgaaatagtccttccttttattgtgtgagg
Downstream sequence
actccatctcaaaaaTATTACATTAAAAAAAGTAAAATTTGTAAAAGAAACAAACAGCATCAGAAAAAATAATATGTTGGTAATTATTTTTTAAAAACTa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate