Basic Information
VIS ID
TVIS10015276
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1624
Orient
-
Integrated sequence
GGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTG| |AACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGT
Host Sequence
Chromosome
chr6
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
30481221/30513444 (Hg38)
End
30481221/30513444 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-3143/Upstream/3365756; hsa-mir-10398/Downstream/70888;
Nearest TSS
ENST00000381078/Upstream/23932; ENST00000415195/Downstream/2822;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/23046, chr6-CpG: 20/Downstream/42065
Nearby gene
LINC02569(+2822) ;
Upstream sequence
TTGATCCTATATTTTTCAATAGATGATCTCATCTTTTTCCATGTGGCCCTCAGCAAGTCTGCTCATTCTTCATCTTCCAAATTTGATTATCAATACCTTT
Downstream sequence
AGAAACAAACAGCATCAGAAAAAATAATATGTTGGTAATTATTTTTTAAAAACTaaaaactaaaaactacaaatctcttctttttctttttcttttttga
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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