Basic Information
VIS ID
TVIS10015278
Fusion event
HBV-LINC01924 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1772
Orient
-
Integrated sequence
CTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTG| |TACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCC
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
61954447/64287212 (Hg38)
End
61954447/64287212 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC01924
Nearest miRNA
hsa-mir-1-2/Upstream/5836054; hsa-mir-5011/Downstream/2794372;
Nearest TSS
ENST00000575820/Upstream/27157; ENST00000578545/Downstream/838498;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/284191, chr18-CpG: 88/Downstream/1463388
Upstream sequence
TTCTCACACCTATATGGTCCCTGTTCTCTTCTCCATCTTATTTCTTTTGGTTTTTACTTTGTATAATGTTCAGAATGTATGTACtttttttttttttttt
Downstream sequence
tttttttttttgagacggagtctcgctctgtcgcccaggctggagtgcagtggcgggatctcggctcactgcaagctccgcctcccgggttcacaccatt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate