VISDB Viral Integration Site DataBase

VIS ID

TVIS10015280

Fusion event

HBV-FN1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

2268

Orient

+

Integrated sequence

CAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTC| |GGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCC

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216299706/215434983 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1676824; hsa-mir-1244-1/Downstream/2465530;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/122574, chr2-CpG: 43/Downstream/561

Upstream sequence

ATTTTCTTCATGTGAATATTGACGTACATATTTTTTTCCTTTTAACTTTGCTAAAAGTTATATACAATGATGTCATTTCCATCTGGCCAGGGGTCTACAT

Downstream sequence

AAAAAAGTTGGAAACATTTTGGAAGGCAGACAATTGAAGTCACATTTTTAAAACATGCAAGGAACTTAAATATTCTTTTGGAGTAATAGTCAAAAAGGAC