VISDB Viral Integration Site DataBase

VIS ID

TVIS10015281

Fusion event

HBV-CYP4A11 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

2797

Orient

+

Integrated sequence

ACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACA| |CATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGAC

Chromosome

chr1

Cytoband

p33

Reference genome

Start

End

47404506/46938834 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4736 ; hsa-mir-3665 ; hsa-mir-7515 ; hsa-mir-3185 ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-9500 ; hsa-mir-6893-5p ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-4690-5p ; hsa-mir-3154 ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-3127-5p ; hsa-mir-6748-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-6880-5p ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-4683 ; hsa-mir-6134 ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-506-5p ; hsa-mir-6757-5p ; hsa-mir-4781-3p

Nearest miRNA

hsa-mir-12136/Upstream/2393282; hsa-mir-101-1/Downstream/4121003;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/219423, chr1-CpG: 40/Downstream/84720

Upstream sequence

AATTTTGAGATTTGGGTTTCTTATTCTCATTTTCACTTATCAACGAATTATGAGCTCCCTGCTGCCTGCAGTCATCTTTCTAAACTCTTCGATGTGGATC

Downstream sequence

ACAAAGCCCTTGGCTTtctggcttcaacttctcttttcttgcctccagccctgctggcaattccaccatcacccgtttgtttcagctccaatgccgatgc