Basic Information
VIS ID
TVIS10015282
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
371
Orient
+
Integrated sequence
TCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTA| |TCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCC
Host Sequence
Chromosome
chr8
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
101905731/100893503 (Hg38)
End
101905731/100893503 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/190479; hsa-mir-10400/Downstream/1231929;
Nearest TSS
ENST00000518652/Upstream/170694; ENST00000514926/Downstream/31485;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/170509, chr8-CpG: 249/Downstream/56913
Nearby gene
RPS26P6(+2237) ;
Upstream sequence
gtccccaggtccgcccctcatcagggtgaccaccaggcctgatactctacatggcagggcctgggcccacaatctgctcccagagactccccgggcaggg
Downstream sequence
cagttgaagtcattttcctaagtcacacagctggaaagcagtggagccaagctccagccctgagttcacatctccatgctgagaagtccttggtcttctt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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