Basic Information
VIS ID
TVIS10015286
Fusion event
HBV-chrX integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp3 X protein
Start
1387
Orient
-
Integrated sequence
CCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGG| |CTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCT
Host Sequence
Chromosome
chrX
Reference genome
GRCh37/hg19
Start
115777227/115777227 (Hg38)
End
115777227/115777227 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/953663; hsa-mir-105-1/Downstream/2609167;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/38429, chrX-CpG: 2749/Downstream/66170
Upstream sequence
aaaatcctcaataaaatactggcaaaccgaatccagcagcacatcaaaaagcttatccaccatgatcaagtgggcttcatccctgggatacaaggctggt
Downstream sequence
acatttggctattaaggttgagataaaacaaaaaatttagttcctcagttgcagtagccatccttcaagtgcttagtagccacttgcagatagtggctac
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate