INPP4B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015287
Fusion event
HBV-INPP4B integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1782
Orient
+
Integrated sequence
TGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGG| |CTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGT
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
143117219/142196066 (Hg38)
End
143117219/142196066 (Hg38)
Orient
+
Location type
Intronic
Target gene
INPP4B
miRNAs that regulate target gene
hsa-mir-222-3p ; hsa-mir-181a-5p ; hsa-mir-765
Nearest miRNA
hsa-mir-12113/Upstream/16688759; hsa-mir-1305/Downstream/1147394;
Nearest TSS
ENST00000502981/Upstream/474284; ENST00000514766/Downstream/109766;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/558896, chr4-CpG: 111/Downstream/649721
Nearest cancer related gene
INPP4B(TSG, No orient, 0)
Upstream sequence
ttttctcacagttctggaggcttgaagtcaaagactaaggtgccagcatgatcagtttctggtgagggcccttcctggattgttgacagcttttttcccc
Downstream sequence
AGCATGTTGTTTGAATAGTCTCCTCCTCTCATAAAAAAGAACTGATTGTTTATTGTTAAATCTAAATGAAGGAGTTTGTGTTTTTTTAGAACCATCTATA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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