Basic Information
VIS ID
TVIS10015288
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
690
Orient
+
Integrated sequence
AAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCA| |TTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCT
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
32068/32068 (Hg38)
End
32068/32068 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Downstream/318089;
Nearest TSS
ENST00000502981/Downstream/21217;
Nearest CpG islands
None/Target, None/Upstream, chr4-CpG: 46/Downstream/21236
Nearby gene
ZNF595(No orient, 21110)
Upstream sequence
GCATAAAAAATGTACTTCAAAATTCATTTCTCTCTGATAAAGGCTCCTGGATTCATGAAGGCGGGTTATAAAAGCATGAATCATGAGGGCTCCCCCATAT
Downstream sequence
GGATGGAGGCTGCTGCTGGAGGAGACAATGTCACTGCAGATGGCTCATGCTGCTCCCATGCTGCAGGGGCCAGTGATTTGGGGCTCCCACCTGCTGTCCC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate