VISDB Viral Integration Site DataBase

VIS ID

TVIS10015289

Fusion event

HBV-ZNF83 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp3 X protein

Start

1621

Orient

-

Integrated sequence

CGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACC| |GTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTT

Chromosome

chr19

Cytoband

q13.41

Reference genome

Start

End

53142158/52638905 (Hg38)

Orient

-

Location type

Promoter

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-340-5p ; hsa-mir-155-5p ; hsa-mir-629-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-329-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-219a-2-3p ; hsa-mir-219b-3p ; hsa-mir-4452 ; hsa-mir-6844 ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-510-3p ; hsa-mir-488-3p ; hsa-mir-1257 ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-4302 ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6845-3p ; hsa-mir-4752 ; hsa-mir-3911 ; hsa-mir-8056 ; hsa-mir-3691-5p ; hsa-mir-376c-5p ; hsa-mir-376b-5p ; hsa-mir-4320 ; hsa-mir-1825 ; hsa-mir-664a-3p ; hsa-mir-4729 ; hsa-mir-29b-2-5p ; hsa-mir-584-5p ; hsa-mir-3193 ; hsa-mir-1539 ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-8076

Nearest miRNA

hsa-let-7e/Upstream/357012; hsa-mir-10394/Downstream/1027774;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/345, chr19-CpG: 59/Downstream/50981

Upstream sequence

TGGGTGAGGTCACCACCTGCGGCTTAAACACAGCTGGGATATgggcgcgggagtgggagcctgaggtcccagctattcaggaagcagcggcgggaggatc

Downstream sequence

gccgagcctgggagttcaggccagcctgggcgacaaagtaacaccccctcccGCAGGGCTCCCTTCCTCGTCTCTCTCTCTCTTTTCTTTTTTATAATAA