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Viral Integration Site DataBase
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TVIS10015330
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015330
Fusion event
HBV-IL6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23740984
Virus Sequence
Virus name
HBV
Reference genome
Not given
Region type
HBVgp3_Xprotein
Start
1782
Host Sequence
Chromosome
chr7
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
22735275/22695656 (Hg38)
End
22735275/22695656 (Hg38)
Location type
5'
Target gene
IL6
miRNAs that regulate target gene
hsa-let-7a-5p
;
hsa-mir-203a-3p
;
hsa-mir-142-3p
;
hsa-mir-26a-5p
;
hsa-mir-335-5p
;
hsa-mir-365a-3p
;
hsa-mir-155-5p
;
hsa-mir-124-3p
;
hsa-mir-1-3p
;
hsa-mir-98-5p
;
hsa-mir-107
;
hsa-let-7c-5p
;
hsa-mir-223-3p
;
hsa-mir-149-5p
;
hsa-let-7f-5p
;
hsa-mir-146b-5p
;
hsa-mir-9-5p
;
hsa-mir-146a-5p
;
hsa-mir-125a-3p
;
hsa-mir-106a-5p
;
hsa-mir-136-5p
;
hsa-mir-451a
Nearest miRNA
hsa-mir-1183/Upstream/1224510; hsa-mir-10399/Downstream/3254263;
Nearest TSS
ENST00000635602/Upstream/30123;
ENST00000426291/Downstream/30228;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/29854
,
chr7-CpG: 25/Downstream/127125
Upstream sequence
tcaacattctgaattgtctaattgtttcctcatggtgcttacctttttcctctatcccctgtgtttcttataaaATAGAAGGTCCCAATCCAAGCAAGAA
Downstream sequence
tctctctttctTTCCGGGAATTGTTGAAGCTTTATGTGTTTCTGCTAGCACAGGTCACATTCTCTAGGGTGTAGTCTTGTGCATGAAGAAATATtttccc
Reference
Khoury, J. D., et al. Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq. J Virol,2013, 87(16): 8916-8926.
Sample Information
×
Sample name
LA3CJ01A
Sample type
Tumor
Gender
Female
CpG Island Information
×
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