DDX18 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015332
Fusion event
HBV-DDX18 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23740984
Virus Sequence
Virus name
HBV
Reference genome
Not given
Region type
HBVgp1_polymerase-1
Start
1330
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
118543485/117785909 (Hg38)
End
118543485/117785909 (Hg38)
Location type
5'
Fragile sites / regions
FRA2S
Target gene
DDX18
miRNAs that regulate target gene
hsa-mir-324-3p ; hsa-mir-128-3p ; hsa-mir-99a-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/4064541; hsa-mir-10b/Downstream/9637628;
Nearest TSS
ENST00000437798/Upstream/1971246; ENST00000489933/Downstream/18265;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2622720, chr2-CpG: 48/Downstream/28627
Upstream sequence
CTGAGGCACCCCTCTCATTTGCACTAGGGATAGTTTATCAGTTGTACTTGTCATTAGAGACTGTGGTCCTTGAAATCAGACAGAAATGCTTTCAGGGCCC
Downstream sequence
CCTGGTGGTGATTTAAAGACCTTGACAGTAAGATCAAAATGTCCATGAATCAAATAAGCTAAGGTAACCAGGTTTTGGAAACTCCTATGTTCTCCAAATG
Reference
Khoury, J. D., et al. Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq. J Virol,2013, 87(16): 8916-8926.
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