Basic Information
VIS ID
TVIS10015380
Fusion event
HBV-DEC1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23867110
Virus Sequence
Virus name
HBV
Reference genome
AB014381.1
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
117939972/115177693 (Hg38)
End
117939972/115177693 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA9E ; FRA9B
Target gene
DEC1
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-let-7a-1/Upstream/968164; hsa-mir-12126/Downstream/5067286;
Nearest TSS
ENST00000422679/Upstream/35875; ENST00000477580/Downstream/76558;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/565897, chr9-CpG: 77/Downstream/976390
Nearest cancer related gene
DEC1(TSG, No orient, 0)
Upstream sequence
cctaataagggaactgggcaggtggggataactaaaaaggagtgcttaaaagagtattgtctaagttggcactagatttggggagttttaagaggtttag
Downstream sequence
TTGTGCCTATCCTGCTTTAAAACCTTCTATCATCTCTCATTTCCTAAAGAATTCCTACCGAGTGCATTAGCTTAGAACTACTCATTCAAggctgggtgtg
Reference
Li, W., et al. HIVID: an efficient method to detect HBV integration using low coverage sequencing. Genomics,2013, 102(4): 338-344.
Curate