Basic Information
VIS ID
TVIS10015391
Fusion event
HBV-chr17 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2013
PubMed ID
23867110
Virus Sequence
Virus name
HBV
Reference genome
AB014381.1
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
14716384/14813067 (Hg38)
End
14716384/14813067 (Hg38)
Fragile sites / regions
FRA17A
Nearest miRNA
hsa-mir-1253/Upstream/1269421; hsa-mir-10226/Downstream/438560;
Nearest TSS
ENST00000595228/Upstream/32864; ENST00000445035/Downstream/21571;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/467663, chr17-CpG: 77/Downstream/447546
Downstream sequence
GTACCAGAATTGGCCCCAATAAATCAGATATTCAGGATGCAGCGCTCACGTCTTTGAGTGTGGTGGTTTCCTTGCAGAATTGTGGGGAACTATGAATGTCCCATAGCATATGGTAGAGTCACAATTATTT
Junction sequence
TGAGGCGCTACGTGTGGACTCTCTTTTATATAAGATCCCCGCCTTCCAAAGAGTGTGTACCAGAATTGGCCCCAATAAATCAGATATTCAGGATGCAGCGCTCACGTCTTTGAGTGTGGTGGTTTCCTTGCAGAATTGTGGGGAACTATGAATGTCCCATAGCATATGGTAGAGTCACAATTATTT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Li, W., et al. HIVID: an efficient method to detect HBV integration using low coverage sequencing. Genomics,2013, 102(4): 338-344.
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