Basic Information
VIS ID
TVIS10015416
Fusion event
HBV-chr2 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2013
PubMed ID
23867110
Virus Sequence
Virus name
HBV
Reference genome
AB014381.1
Host Sequence
Chromosome
chr2
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
204666726/203802003 (Hg38)
End
204666726/203802003 (Hg38)
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/14668892; hsa-mir-1244-1/Downstream/2981231;
Nearest TSS
ENST00000437798/Upstream/95455; ENST00000295854/Downstream/65783;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/266557, chr2-CpG: 83/Downstream/743213
Upstream sequence
TTCTTCCCCCACCGAGGAGAGCATCAGCCAGCGAGATGATGAAGTCTTCTGGTGAGGACACCTCCTAGGGACTAGACAGGCTAACTTCTTGGTCCCATCC
Downstream sequence
GGTAAAATAAGCTGCAGGTTATGTGCTATTTCTGGAGTTTTGGGGTAAATTTGTGCCTTGCTTTCCTGCTCAAGCAAAT
Junction sequence
TTCTTCCCCCACCGAGGAGAGCATCAGCCAGCGAGATGATGAAGTCTTCTGGTGAGGACACCTCCTAGGGACTAGACAGGCTAACTTCTTGGTCCCATCCTCTTTAAGGGGCCCCACAAATTGCTTACATCTATCAACAATGTCCTCCTGCAAATGAATGTCAGGAAAAGAAGGAGTTTGCCATTTAGGATTAAAGCAAGGTACCGTAGAAGAATACAGCCCCGTAAAGGTAAAATAAGCTGCAGGTTATGTGCTATTTCTGGAGTTTTGGGGTAAATTTGTGCCTTGCTTTCCTGCTCAAGCAAAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Li, W., et al. HIVID: an efficient method to detect HBV integration using low coverage sequencing. Genomics,2013, 102(4): 338-344.
Curate