Basic Information
VIS ID
TVIS10015422
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2013
PubMed ID
23867110
Virus Sequence
Virus name
HBV
Reference genome
AB014381.1
Host Sequence
Chromosome
chr1
Cytoband
p36.32
Reference genome
GRCh37/hg19
Start
5019596/4959536 (Hg38)
End
5019596/4959536 (Hg38)
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/1398746; hsa-mir-101-1/Downstream/903136;
Nearest TSS
ENST00000473358/Upstream/248381; ENST00000641403/Downstream/13762;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/187043, chr1-CpG: 43/Downstream/752460
Downstream sequence
GCAGGCGTCCTTTCCAAGGACCTACAGGATCACCATGGGCCTAGCAGATAAACCAGGATGATGTCCATATTTTAAAGTTCATAGCCTTAATTCTGTCTGCAAACTCCCTATTGCCACGTAACAGCATATATACAGGTTTCTGGGATTAGAGTGTGGGCAACTTTAGT
Junction sequence
GAGGCTGTAGGCATAAATTGGTCTGTTCACCGCAGGCGTCCTTTCCAAGGACCTACAGGATCACCATGGGCCTAGCAGATAAACCAGGATGATGTCCATATTTTAAAGTTCATAGCCTTAATTCTGTCTGCAAACTCCCTATTGCCACGTAACAGCATATATACAGGTTTCTGGGATTAGAGTGTGGGCAACTTTAGT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Li, W., et al. HIVID: an efficient method to detect HBV integration using low coverage sequencing. Genomics,2013, 102(4): 338-344.
Curate