Basic Information
VIS ID
TVIS10015449
Fusion event
HBV-IGK integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23867110
Virus Sequence
Virus name
HBV
Reference genome
AB014381.1
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
89879976/89841166 (Hg38)
End
89879976/89841166 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
IGK
Nearest miRNA
hsa-mir-1285-2/Upstream/1028712; hsa-mir-10b/Downstream/6957112;
Nearest TSS
ENST00000437798/Upstream/510737; ENST00000429992/Downstream/10625;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/73065, chr2-CpG: 65/Downstream/396882
Upstream sequence
tttcccatcactcctaaaaaggaaccctgtacccatgagcagtcacacctcgctcactcctccctcattcctggaaatcgctaatctactttcggtctct
Downstream sequence
atgggatggaatggaatgAGGGAATGTCATTGAGCAATGAAGGAATGTCATCCTTACCCAGATGCCAGCCACCTGTCTCACATCCAGGACAGAGTCTCCA
Reference
Li, W., et al. HIVID: an efficient method to detect HBV integration using low coverage sequencing. Genomics,2013, 102(4): 338-344.
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