Basic Information
VIS ID
TVIS10015569
Fusion event
HBV-LOC730100 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Host Sequence
Chromosome
chr2
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
51654161/51427023 (Hg38)
End
51654161/51427023 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC730100
Nearest miRNA
hsa-mir-1301/Upstream/730761; hsa-mir-10b/Downstream/1275499;
Nearest TSS
ENST00000437798/Upstream/201448; ENST00000435357/Downstream/946095;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/398663, chr2-CpG: 118/Downstream/1144242
Upstream sequence
GAAAGAATGAATAAGGCCTAGTACTTGGTAGCACAATGGGGTGACTGTACT
Junction sequence
GAAAGAATGAATAAGGCCTAGTACTTGGTAGCACAATGGGGTGACTGTACTTTGCATGGTGCTGGTGAACACACCAATTTATGCCTAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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