Basic Information
VIS ID
TVIS10015581
Fusion event
HBV-chr22 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
43501663/43105657 (Hg38)
End
43501663/43105657 (Hg38)
Orient
+
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-mir-1281/Upstream/1182360; hsa-let-7a-3/Downstream/2095297;
Nearest TSS
ENST00000624155/Upstream/16229; ENST00000216115/Downstream/5091;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/16118, chr22-CpG: 19/Downstream/4288
Nearby gene
BIK ;
Nearest cancer related gene
BIK(TSG, -) ;
Upstream sequence
GAACTCCTGGCCTCAAGTGATCAGCCCACCTCCA
Junction sequence
GAACTCCTGGCCTCAAGTGATCAGCCCACCTCCACCTCCTAGTACAAAGACCTTTAACCTAATCTCCTCCCCCAACTCCTCCCACTCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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