Basic Information
VIS ID
TVIS10015598
Fusion event
HBV-chr8 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr8
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
41175965/41318446 (Hg38)
End
41175965/41318446 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-124-1/Upstream/47303; hsa-mir-10400/Downstream/341995;
Nearest TSS
ENST00000518652/Upstream/8949; ENST00000521725/Downstream/116852;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/8825, chr8-CpG: 69/Downstream/171829
Nearby gene
SFRP1 ;
Nearest cancer related gene
SFRP1(TSG, -) ;
Upstream sequence
ATGGTTGCCAGAGAGCTGCTGTACCTCAGGCATCACAGCTAAATTCCAGGTGG
Junction sequence
ATGGTTGCCAGAGAGCTGCTGTACCTCAGGCATCACAGCTAAATTCCAGGTGGGGTGAACGCACCACTTTATGCCTACAGCCTCCTAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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