Basic Information
VIS ID
TVIS10015603
Fusion event
HBV-BICRAL integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
42737115/42769377 (Hg38)
End
42737115/42769377 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
BICRAL
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-192-5p ; hsa-mir-4526 ; hsa-mir-4504 ; hsa-mir-6721-5p ; hsa-mir-5191 ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-7854-3p ; hsa-mir-135a-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-9500 ; hsa-mir-6750-5p ; hsa-mir-6822-5p ; hsa-mir-5584-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4311 ; hsa-mir-200a-3p ; hsa-mir-141-3p
Nearest miRNA
hsa-mir-10398/Upstream/1035767; hsa-mir-10524/Downstream/665165;
Nearest TSS
ENST00000381078/Upstream/22419; ENST00000394168/Downstream/12650;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/22073, chr6-CpG: 77/Downstream/13627
Nearby gene
TBCC ;
Upstream sequence
GGTTGGTTTGGGTGACCAATAGGATAGGGCAGAAGCTTCCCATCTTGGGTGCTCTC
Junction sequence
GGTTGGTTTGGGTGACCAATAGGATAGGGCAGAAGCTTCCCATCTTGGGTGCTCTCAAAAGTTGCATGGTGCTGGTGAACACACCAAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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