Basic Information
VIS ID
TVIS10015623
Fusion event
HBV-LRMDA integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr10
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
77459368/75699610 (Hg38)
End
77459368/75699610 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
LRMDA
Nearest miRNA
hsa-mir-1265/Upstream/147057; hsa-mir-107/Downstream/10565084;
Nearest TSS
ENST00000439456/Upstream/52101; ENST00000611306/Downstream/83151;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/267797, chr10-CpG: 19/Downstream/412715
Nearby gene
LRMDA ;
Upstream sequence
AATCATGATACTCTTTTTCAGCCTCATTAACCAGTCACAAT
Junction sequence
AATCATGATACTCTTTTTCAGCCTCATTAACCAGTCACAATTTATGCCTACAGCCTCCTAGTACAAAGACCTTTAACCTAATCTCCTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
Curate