Basic Information
VIS ID
TVIS10015633
Fusion event
HBV-ARHGAP44 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
12767992/12864675 (Hg38)
End
12767992/12864675 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA17A
Target gene
ARHGAP44
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-30c-5p
Nearest miRNA
hsa-mir-1253/Upstream/782679; hsa-mir-10226/Downstream/52593;
Nearest TSS
ENST00000595228/Upstream/74184; ENST00000616670/Downstream/79445;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/74302, chr17-CpG: 44/Downstream/109278
Upstream sequence
TCTCCTTATTCAGTTCTATTTCAATAGCTGCCATATTTTCTAGTTTAG
Junction sequence
TCTCCTTATTCAGTTCTATTTCAATAGCTGCCATATTTTCTAGTTTAGAGTCTCCTCCCCCAACTCCTCCCAGTCTTTAAACACACAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
Curate