Basic Information
VIS ID
TVIS10015636
Fusion event
HBV-LACTBL1 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
23288211/22961718 (Hg38)
End
23288211/22961718 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
LACTBL1
Nearest miRNA
hsa-mir-12136/Upstream/98492; hsa-mir-101-1/Downstream/82587;
Nearest TSS
ENST00000473358/Upstream/96559; ENST00000481879/Downstream/1460;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/7642, chr1-CpG: 80/Downstream/57603
Nearby gene
EPHB2(+) ;
Upstream sequence
AGGGATGGGGAGTGGAGGTGGACCGAGCTCAGCC
Junction sequence
AGGGATGGGGAGTGGAGGTGGACCGAGCTCAGCCGGTGAACAGACCAATTTATGCCTACAGCCTCCTAGTACAAAGATCATTAACCTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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