IL12B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015661
Fusion event
HBV-IL12B integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
158753310/159326302 (Hg38)
End
158753310/159326302 (Hg38)
Orient
+
Location type
Intronic
Target gene
IL12B
miRNAs that regulate target gene
hsa-mir-4284 ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-103b ; hsa-mir-4705 ; hsa-mir-3614-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-10397/Upstream/4496762; hsa-mir-103a-1/Downstream/1148100;
Nearest TSS
ENST00000502646/Upstream/15369; ENST00000515337/Downstream/4585;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/62769, chr5-CpG: 37/Downstream/5164
Upstream sequence
TTCCACCACATGATACTGCCCCCTCAGTTGGCA
Junction sequence
TTCCACCACATGATACTGCCCCCTCAGTTGGCAGTATCAAGGGATACAAACAGTCTTTGAAGGACGCCTCAAGGTCTGACGTTGACAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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