Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015665
Fusion event
HBV-ZBTB16 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
-
Host Sequence
Chromosome
chr11
Cytoband
q23.2
Reference genome
End
113964191/114093469 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-5580-3p ; hsa-mir-190a-3p ; hsa-mir-301b-3p ; hsa-mir-3145-3p ; hsa-mir-186-3p ; hsa-mir-5685 ; hsa-mir-4699-3p ; hsa-mir-4690-3p ; hsa-mir-3908 ; hsa-mir-330-3p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-15a-5p ; hsa-mir-6838-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6749-3p ; hsa-mir-452-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-5088-3p ; hsa-mir-5193 ; hsa-mir-1470 ; hsa-mir-4667-3p ; hsa-mir-1306-5p ; hsa-mir-5011-5p ; hsa-mir-6778-3p ; hsa-mir-3162-3p ; hsa-mir-361-3p ; hsa-mir-6849-3p
Nearest miRNA
hsa-mir-10392/Upstream/643381; hsa-let-7a-2/Downstream/4550531;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/10352, chr11-CpG: 24/Downstream/105672
Nearest cancer related gene
ZBTB16(TSG, No orient, 0)
Upstream sequence
CCACTACACTCAGCCCTGCTGCTGCTTCCAAGGGACAACTCCCTCTC
Junction sequence
CCACTACACTCAGCCCTGCTGCTGCTTCCAAGGGACAACTCCCTCTCTGCTGGTGAACAGACCAATTTATGCCTCCAGTCTCCTAGTA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.