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VISDB
Viral Integration Site DataBase
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TVIS10015681
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015681
Fusion event
HBV-TAF2 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
120776729/119764489 (Hg38)
End
120776729/119764489 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8C
;
FRA8E
Target gene
TAF2
miRNAs that regulate target gene
hsa-mir-181a-5p
;
hsa-mir-4803
;
hsa-mir-6739-3p
;
hsa-mir-375
;
hsa-mir-6844
;
hsa-mir-6853-3p
;
hsa-mir-1206
;
hsa-mir-3148
;
hsa-mir-651-3p
Nearest miRNA
hsa-mir-12123/Upstream/439224; hsa-mir-10400/Downstream/3451299;
Nearest TSS
ENST00000518652/Upstream/1581;
ENST00000518057/Downstream/2639;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/347551
,
chr8-CpG: 29/Downstream/68069
Upstream sequence
CCATGTTACTTTACAGCATTCCATTATGCTTGTGA
Junction sequence
CCATGTTACTTTACAGCATTCCATTATGCTTGTGATGAAAAAGTTGCATGGTGCTGGTGAACAGACCAATTTATGCCTAAAGCCTCAT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
Sample Information
×
Sample name
N102
Sample type
Adjacent tissue
Gender
Female
CpG Island Information
×
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