VISDB - VIS Detail

Expression analysis of TCGA samples

Basic Information

VIS ID

TVIS10015686

Fusion event

HBV-CDC27 integration

Validated

No

Detection method

MAPS

Data source

Curated

Sample type

Adjacent tissue

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2012

PubMed ID

23236287

Virus Sequence

Virus name

HBV

Reference genome

AY800389.1;AY800390.1;AY800391.1;AY800392.1

Orient

-

Host Sequence

Chromosome

chr17

Cytoband

q21.32

Reference genome

GRCh37/hg19

Start

45213097/47135731 (Hg38)

End

45213097/47135731 (Hg38)

Orient

-

Location type

Intronic

Target gene

CDC27

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-32-5p ; hsa-mir-16-5p ; hsa-mir-223-3p ; hsa-mir-539-5p ; hsa-mir-4470 ; hsa-mir-491-3p ; hsa-mir-4275 ; hsa-mir-767-5p ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-3148 ; hsa-mir-3917 ; hsa-mir-590-3p ; hsa-mir-4282 ; hsa-mir-548c-3p ; hsa-mir-3074-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-1283 ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-944 ; hsa-mir-10a-3p ; hsa-mir-1253 ; hsa-mir-5579-5p ; hsa-mir-5197-3p ; hsa-mir-4311 ; hsa-mir-5583-3p ; hsa-mir-5701 ; hsa-mir-5588-5p ; hsa-mir-4799-3p ; hsa-mir-4720-5p ; hsa-mir-6868-5p ; hsa-mir-3128 ; hsa-mir-3126-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-218-2-3p ; hsa-mir-27a-3p

Nearest miRNA

hsa-mir-1180/Upstream/162631; hsa-mir-10226/Downstream/897151;

Nearest TSS

ENST00000595228/Upstream/11836; ENST00000572193/Downstream/1513;

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/35342, chr17-CpG: 64/Downstream/53154

Upstream sequence

AGTAAAAGCTGGCCAATCTGAATAATCCTCCTTTAAACAAACACAATTTTTGATAGGGTT

Junction sequence

AGTAAAAGCTGGCCAATCTGAATAATCCTCCTTTAAACAAACACAATTTTTGATAGGGTTAAGTTGCATGGTGCTGGTGTGCACAACA

* Color: Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence

Reference

Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.