Basic Information
VIS ID
TVIS10015693
Fusion event
HBV-chr10 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr10
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
130051027/128252763 (Hg38)
End
130051027/128252763 (Hg38)
Orient
+
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/2432941; hsa-mir-202/Downstream/1590536;
Nearest TSS
ENST00000439456/Upstream/71627; ENST00000446589/Downstream/67451;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/41407, chr10-CpG: 33/Downstream/12940
Nearby gene
MKI67 ;
Upstream sequence
GCCACAACCTGATGCCTGTCTGGTAGAGAAATGTTTC
Junction sequence
GCCACAACCTGATGCCTGTCTGGTAGAGAAATGTTTCTTATGCCTACAGCCTCCTAATACAAAGACCTTTAAACTAATCTCCTCCCCC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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