Basic Information
VIS ID
TVIS10015699
Fusion event
HBV-chr22 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
36670131/36274085 (Hg38)
End
36670131/36274085 (Hg38)
Orient
+
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-mir-1286/Upstream/937286; hsa-let-7a-3/Downstream/12762;
Nearest TSS
ENST00000624155/Upstream/20921; ENST00000424761/Downstream/11936;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/207722, chr22-CpG: 24/Downstream/48320
Nearby gene
APOL1(+) ;
Upstream sequence
AAATCTCTCCAAGGACATGAGTTTGATTTTTTCAAATTGTCCATT
Junction sequence
AAATCTCTCCAAGGACATGAGTTTGATTTTTTCAAATTGTCCATTTGCTGGTGAACACACCAATTTATGCCTACAGCCTCCTAGTACA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
Curate