Basic Information
VIS ID
TVIS10015729
Fusion event
HBV-chr1 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
-
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
75563398/75097714 (Hg38)
End
75563398/75097714 (Hg38)
Orient
-
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/4029998; hsa-mir-11399/Downstream/1962429;
Nearest TSS
ENST00000473358/Upstream/134400; ENST00000607240/Downstream/26213;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/899363, chr1-CpG: 40/Downstream/27418
Nearby gene
LHX8 ;
Upstream sequence
CCAAGGGCAGAACAAAAGCCTAGCCTAGAGGGAAAAAAAAA
Junction sequence
CCAAGGGCAGAACAAAAGCCTAGCCTAGAGGGAAAAAAAAATTGAAAAAGTTGCATGGTGCTGGTGAACAGACCAATTTATGCCTACA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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