PRKDC _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015738
Fusion event
HBV-PRKDC integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr8
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
48815058/47902498 (Hg38)
End
48815058/47902498 (Hg38)
Orient
+
Location type
Intronic
Target gene
PRKDC
miRNAs that regulate target gene
hsa-mir-101-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-124-1/Upstream/5006223; hsa-mir-10400/Downstream/13812290;
Nearest TSS
ENST00000518652/Upstream/37706; ENST00000520994/Downstream/26671;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/70882, chr8-CpG: 36/Downstream/57400
Upstream sequence
GTTTTGAAAGGTGACTTGGAGTTTCACTCTGTGT
Junction sequence
GTTTTGAAAGGTGACTTGGAGTTTCACTCTGTGTAGACCTTTAACCTAATCTCCTCCCCCAACTCCTCCCAGTCTTTAAACAAACAGT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
Curate