Basic Information
VIS ID
TVIS10015750
Fusion event
HBV-chr13 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
59921279/59347145 (Hg38)
End
59921279/59347145 (Hg38)
Orient
-
Fragile sites / regions
FRA13B ; FRA13C
Nearest miRNA
hsa-mir-1297/Upstream/4172597; hsa-mir-1267/Downstream/1852653;
Nearest TSS
ENST00000623511/Upstream/1114028; ENST00000435636/Downstream/349048;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1712349, chr13-CpG: 52/Downstream/816381
Upstream sequence
TCAGAGGCAGTTCTGCAATCATATTTATACCTACTTGTAATTACATGTAAATTAAAGGGTGGATT
Junction sequence
TCAGAGGCAGTTCTGCAATCATATTTATACCTACTTGTAATTACATGTAAATTAAAGGGTGGATTACCTAATCTCCTCCACCAACTCC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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